This chapter reviews the research that examines the brain more directly via brain imaging. The clinical implications of this research are significant. For instance, neuroimaging studies of psychopathy have implemented a variety of brain imaging techniques and paradigms to uncover the brain regions in which the structure or functioning is different in psychopathy. These studies primarily implicate the amygdala and orbitofrontal cortex as the brain structures that function differently in psychopathy, though several additional regions involved in important processes such as moral judgment have been identified. In addition, studies conducted through brain imaging in children with psychopathic traits suggest that alterations in the brain may originate early in life.
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