The U.S. has been the preeminent power in Latin America in terms of military capability, foreign investment, and cultural ties. The growing presence of China in Latin America prompted agricultural and raw material exports of LAC countries. However, with the Chinese economy slowing down, the trade balance has turned against the LAC countries and China’s economic role is seen as a mixed blessing. The split in LAC states on their varying attitudes toward the U.S. complicated the relationship between the LAC region and the outside powers. The Chinese have built on the skepticism and resentment toward the U.S. and have widened the coalition of anti-U.S. states as regimes with related views arose in Argentina, Brazil, Bolivia, and Venezuela. This volume looks into key cross-regional trends and critical policy issues involving the changing relationship between China, the U.S., and LAC states. Case studies into recent political and economic developments in Mexico, Venezuela, Brazil, Argentina, the Andes, and the Caribbean provide a more in-depth analysis of the implications of China’s and the U.S.’s evolving interaction with the region.